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There have
been a number of false claims about the biological activity of pangamic
acid, a derivative of the amino acid glycine (pangamic acid is dimethyl
glycine). This substance has been reported to be an oxygenator of body
tissues, and also as an excellent scavenger of free radicals. As a
nutritional supplement, products properly labeled as DMG or
Dimethylglycine may have some use as an aid to increased exercise
endurance, oxygenation of tissues, and as a free radical scavenger. In
spite of it's proven effects in scattered small clinical studies, and
reports of use during the Olympic Games, safety studies are not yet
complete. Until further safety data is available, it is recommended that
pregnant women and lactating women avoid the use of this supplement. It is
further advised that everyone avoid products labeled as "pangamic
acid", or "calcium pangamate", which are impure derivatives
of this product. Although DMG is not an essential nutrient in humans, the
recommended dosage to achieve increased exercise performance is 50-125 mgs
daily.
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